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Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)

National Institutes of Health

RFA-DA-26-001

HHS-NIH11

General Information

Est. Program Funding:

March 19, 2026

Closing Date:

Expected No. of Awards

$350,000

Award Ceiling

Opportunity Number:
RFA-DA-26-001

Owning Agency:
HHS-NIH11

Opportunity Category:
Discretionary (D)

Synopsis

The purpose of this notice of funding opportunity (NOFO) is to support data mining of single cell data sets to identify cell types, transcripts, enhancers, or transcriptional networks that play a role in HIV/antiretroviral therapy (ART) or Substance Use Disorder (SUD)-relevant molecular responses, and/or to support functional validation studies (e.g. epigenomic or transcriptomic manipulation, high throughput secondary screening) to confirm or deny a biological role for one or more of the data-mined cell types, transcripts, enhancers, or transcriptional networks in HIV/ART and SUD molecular responses.

Response Date	Mar 19, 2026 12:00:00 AM EDT
Posting Date	Aug 14, 2024 12:00:00 AM EDT
Archive Date	Apr 24, 2026 12:00:00 AM EDT
Award Ceiling	350,000
Award Floor
Cost Sharing	No

Eligibility

Eligible Applicants

City or township governments, Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, For profit organizations other than small businesses, State governments, Native American tribal organizations (other than Federally recognized tribal governments), County governments, Public and State controlled institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Small businesses, Native American tribal governments (Federally recognized), Independent school districts

Additional Info on Eligibility:

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-001.html
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

93.279: Drug Abuse and Addiction Research Programs
:

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