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Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)

National Institutes of Health

PAR-25-063

HHS-NIH11

General Information

Est. Program Funding:

May 7, 2026

Closing Date:

Expected No. of Awards

Award Ceiling

Opportunity Number:
PAR-25-063

Owning Agency:
HHS-NIH11

Opportunity Category:
Discretionary (D)

Synopsis

The objective of this Notice of Funding Opportunity (NOFO) is to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to psychiatric disorders; and 2) to generate new insight into the biology of relevant diseases and processes that have yet to be validated as important drug targets.

Response Date	May 07, 2026 12:00:00 AM EDT
Posting Date	Nov 06, 2024 12:00:00 AM EST
Archive Date	Jun 12, 2026 12:00:00 AM EDT
Award Ceiling
Award Floor
Cost Sharing	No

Eligibility

Eligible Applicants

Native American tribal governments (Federally recognized), Independent school districts, Small businesses, Public and State controlled institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Native American tribal organizations (other than Federally recognized tribal governments), City or township governments, For profit organizations other than small businesses, Public housing authorities/Indian housing authorities, State governments, Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, County governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Additional Info on Eligibility:

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	https://grants.nih.gov/grants/guide/pa-files/PAR-25-063.html
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

93.242: Mental Health Research Grants
:

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