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Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)

National Institutes of Health

PAR-25-362

HHS-NIH11

General Information

Est. Program Funding:

January 7, 2029

Closing Date:

Expected No. of Awards

$400,000

Award Ceiling

Opportunity Number:
PAR-25-362

Owning Agency:
HHS-NIH11

Opportunity Category:
Discretionary (D)

Synopsis

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune development in utero, during the early post-natal period and during early childhood in neonates, infants, and children and adolescents with or without in-utero exposure to HIV or Anti-Retroviral Therapeutics (ART).This initiative aims to understand intricate mechanisms of immune cells at the maternal-fetal interface, T and B cell development and maturation in offspring, and local immune responses and the role of systemic immunity.

Response Date	May 07, 2026 12:00:00 AM EDT
Posting Date	Dec 30, 2024 12:00:00 AM EST
Archive Date	Jul 06, 2026 12:00:00 AM EDT
Award Ceiling	400,000
Award Floor
Cost Sharing	No

Eligibility

Eligible Applicants

Public and State controlled institutions of higher education, Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, City or township governments, Small businesses, Independent school districts, Native American tribal governments (Federally recognized), Others (see text field entitled "Additional Information on Eligibility" for clarification), County governments, For profit organizations other than small businesses, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Private institutions of higher education

Additional Info on Eligibility:

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	https://grants.nih.gov/grants/guide/pa-files/PAR-25-362.html
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

93.865: Child Health and Human Development Extramural Research
:

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