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Total Dollar Available
$ 100 Trillion

Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)

Deadline: May 7, 2026

Opportunity Number: PAR-25-362

Agency: National Institutes of Health

Open Date: December 30, 2024

Close Date: May 7, 2026

Status: Posted

CFDA Numbers: 93.865

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Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PAR-25-283

Agency: National Institutes of Health

Open Date: December 30, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.242

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Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PAR-25-284

Agency: National Institutes of Health

Open Date: December 30, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.242

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Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)

Deadline: May 7, 2028

Opportunity Number: PAR-25-374

Agency: National Institutes of Health

Open Date: December 30, 2024

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.866

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NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

Deadline: January 7, 2027

Opportunity Number: PAR-25-032

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2027

Status: Posted

CFDA Numbers: 93.838, 93.840, 93.839, 93.233, 93.837

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NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required)

Deadline: January 7, 2028

Opportunity Number: PA-25-307

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.865, 93.273, 93.213, 93.361, 93.242, 93.279, 93.866, 93.233, 93.837, 93.173, 93.838, 93.839, 93.840, 93.867

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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PA-25-304

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.143, 93.286, 93.838, 93.399, 93.213, 93.837, 93.879, 93.866, 93.242, 93.393, 93.233, 93.113, 93.865, 93.273, 93.395, 93.172, 93.396, 93.840, 93.121, 93.394, 93.310, 93.839, 93.307, 93.855, 93.173, 93.361, 93.867, 93.279, 93.846

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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

Deadline: January 7, 2028

Opportunity Number: PA-25-306

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.213, 93.393, 93.855, 93.840, 93.273, 93.846, 93.286, 93.399, 93.279, 93.113, 93.172, 93.307, 93.838, 93.233, 93.839, 93.866, 93.143, 93.173, 93.837, 93.395, 93.865, 93.394, 93.879, 93.242, 93.396, 93.361, 93.867

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NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)

Deadline: January 7, 2028

Opportunity Number: PA-25-303

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.839, 93.361, 93.307, 93.173, 93.853, 93.865, 93.866, 93.233, 93.837, 93.121, 93.867, 93.399, 93.847, 93.213, 93.279, 93.242, 93.113, 93.273, 93.840, 93.838

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NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PA-25-301

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.361, 93.395, 93.396, 93.351, 93.837, 93.846, 93.121, 93.839, 93.879, 93.859, 93.286, 93.838, 93.867, 93.394, 93.233, 93.847, 93.307, 93.143, 93.853, 93.279, 93.213, 93.273, 93.399, 93.866, 93.242, 93.113, 93.393, 93.840, 93.855, 93.865, 93.172

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NIH Research Project Grant (Parent R01 Clinical Trial Required)

Deadline: January 7, 2028

Opportunity Number: PA-25-305

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.233, 93.113, 93.279, 93.859, 93.839, 93.846, 93.213, 93.273, 93.286, 93.307, 93.847, 93.867, 93.838, 93.853, 93.855, 93.866, 93.173, 93.840, 93.837, 93.879, 93.865, 93.242, 93.361, 93.143, 93.172

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NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PA-25-302

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.839, 93.310, 93.855, 93.113, 93.866, 93.879, 93.837, 93.143, 93.172, 93.853, 93.233, 93.286, 93.840, 93.865, 93.273, 93.242, 93.279, 93.838

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Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)

Deadline: October 8, 2027

Opportunity Number: PAR-25-327

Agency: National Institutes of Health

Open Date: December 18, 2024

Close Date: October 8, 2027

Status: Posted

CFDA Numbers: 93.853

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D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)

Deadline: September 7, 2027

Opportunity Number: PAS-25-236

Agency: National Institutes of Health

Open Date: December 16, 2024

Close Date: September 7, 2027

Status: Posted

CFDA Numbers: 93.279

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Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)

Deadline: November 15, 2027

Opportunity Number: PAR-25-311

Agency: National Institutes of Health

Open Date: December 16, 2024

Close Date: November 15, 2027

Status: Posted

CFDA Numbers: 93.865, 93.313

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NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

Deadline: October 12, 2027

Opportunity Number: RFA-DC-25-002

Agency: National Institutes of Health

Open Date: December 16, 2024

Close Date: October 12, 2027

Status: Posted

CFDA Numbers: 93.173

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Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)

Deadline: February 26, 2027

Opportunity Number: RFA-HG-25-009

Agency: National Institutes of Health

Open Date: December 16, 2024

Close Date: February 26, 2027

Status: Posted

CFDA Numbers: 93.172

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Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

Deadline: November 15, 2027

Opportunity Number: PAR-25-336

Agency: National Institutes of Health

Open Date: December 16, 2024

Close Date: November 15, 2027

Status: Posted

CFDA Numbers: 93.395

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Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (T32 Clinical Trial Not Allowed)

Deadline: September 25, 2026

Opportunity Number: PAR-25-247

Agency: National Institutes of Health

Open Date: December 13, 2024

Close Date: September 25, 2026

Status: Posted

CFDA Numbers: 93.866

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Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)

Deadline: September 10, 2027

Opportunity Number: PAR-25-325

Agency: National Institutes of Health

Open Date: December 13, 2024

Close Date: September 10, 2027

Status: Posted

CFDA Numbers: 93.393

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Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

Deadline: May 8, 2027

Opportunity Number: PAR-25-317

Agency: National Institutes of Health

Open Date: December 13, 2024

Close Date: May 8, 2027

Status: Posted

CFDA Numbers: 93.313, 93.307, 93.399, 93.273, 93.310, 93.361

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Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

Deadline: January 7, 2028

Opportunity Number: PAR-25-346

Agency: National Institutes of Health

Open Date: December 11, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.394, 93.393, 93.121, 93.396, 93.395, 93.399

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HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)

Deadline: July 16, 2026

Opportunity Number: PAR-25-154

Agency: National Institutes of Health

Open Date: December 11, 2024

Close Date: July 16, 2026

Status: Posted

CFDA Numbers: 93.853, 93.846, 93.273, 93.865, 93.866, 93.121, 93.213, 93.279, 93.350

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Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

Deadline: October 19, 2026

Opportunity Number: PAR-25-155

Agency: National Institutes of Health

Open Date: December 11, 2024

Close Date: October 19, 2026

Status: Posted

CFDA Numbers: 93.350

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Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)

Deadline: June 18, 2026

Opportunity Number: PAR-25-157

Agency: National Institutes of Health

Open Date: December 10, 2024

Close Date: June 18, 2026

Status: Posted

CFDA Numbers: 93.350

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