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Total Dollars Available
$ 100 Trillion

BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

Deadline: October 4, 2027


Opportunity Number: RFA-NS-27-015

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: October 4, 2027

Status: Posted

CFDA Numbers: 93.279, 93.242, 93.853, 93.867, 93.286, 93.372, 93.866, 93.865, 93.173, 93.213, 93.273

Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)

Deadline: July 16, 2029


Opportunity Number: PAR-27-074

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: July 16, 2029

Status: Posted

CFDA Numbers: 93.846

Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)

Deadline: December 2, 2026


Opportunity Number: RFA-OD-27-008

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: December 2, 2026

Status: Posted

CFDA Numbers: 93.310, 93.121, 93.853, 93.313, 93.361, 93.307

NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

Deadline: April 5, 2029


Opportunity Number: PA-27-101

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: April 5, 2029

Status: Posted

CFDA Numbers: 93.853, 93.838, 93.839, 93.866, 93.307, 93.847, 93.394, 93.837, 93.855, 93.313, 93.393, 93.865, 93.350, 93.242, 93.867, 93.233, 93.351, 93.840, 93.859, 93.273, 93.395

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Deadline: April 5, 2027


Opportunity Number: PA-27-102

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: April 5, 2027

Status: Posted

CFDA Numbers: 93.837, 93.859, 93.840, 93.313, 93.242, 93.279, 93.286, 93.847, 93.879, 93.846, 93.361, 93.173, 93.394, 93.853, 93.213, 93.307, 93.838, 93.351, 93.393, 93.395, 93.866, 93.273, 93.865, 93.350, 93.172, 93.839, 93.233, 93.121, 93.867, 93.113, 93.855

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Deadline: April 5, 2027


Opportunity Number: PA-27-100

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: April 5, 2027

Status: Posted

CFDA Numbers: 93.143, 93.286, 93.394, 93.865, 93.350, 93.068, 93.853, 93.361, 93.307, 93.103, 93.395, 93.273, 93.846, 93.855, 93.142, 93.213, 93.073, 93.233, 93.866, 93.351, 93.837, 93.847, 93.840, 93.313, 93.242, 93.879, 93.393, 93.859, 93.172, 93.173, 93.839, 93.083, 93.136, 93.070, 93.084, 93.326, 93.838, 93.867, 93.279, 93.121, 93.113

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Deadline: April 5, 2029


Opportunity Number: PAR-27-098

Agency: National Institutes of Health

Open Date: May 28, 2026

Close Date: April 5, 2029

Status: Posted

CFDA Numbers: 93.307, 93.313, 93.865, 93.838, 93.242, 93.233, 93.273, 93.173, 93.853, 93.393, 93.395, 93.350, 93.866, 93.121, 93.867, 93.113, 93.855, 93.859, 93.172, 93.839, 93.840, 93.286, 93.846, 93.143, 93.351, 93.394, 93.837, 93.847

Academic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)

Deadline: July 12, 2029


Opportunity Number: PAR-27-062

Agency: National Institutes of Health

Open Date: May 27, 2026

Close Date: July 12, 2029

Status: Posted

CFDA Numbers: 93.855, 93.398, 93.121, 93.286, 93.853

Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

Deadline: January 26, 2029


Opportunity Number: PAR-27-067

Agency: National Institutes of Health

Open Date: May 27, 2026

Close Date: January 26, 2029

Status: Posted

CFDA Numbers: 93.286, 93.173, 93.853, 93.867, 93.351, 93.846, 93.866, 93.859, 93.121, 93.172, 93.242

NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation

Deadline: November 4, 2026


Opportunity Number: 26-511

Agency: U.S. National Science Foundation

Open Date: May 22, 2026

Close Date: November 4, 2026

Status: Posted

CFDA Numbers: 47.084

DoW Toxic Exposures Clinical Trial Award

Deadline: November 19, 2026


Opportunity Number: HT942526TERPCTA

Agency: Defense Health Agency Contracting Activity - DHACA

Open Date: May 21, 2026

Close Date: November 19, 2026

Status: Posted

CFDA Numbers: 12.420

DoW Toxic Exposures Investigator Initiated Research Award

Deadline: November 19, 2026


Opportunity Number: HT942526TERPIIRA

Agency: Defense Health Agency Contracting Activity - DHACA

Open Date: May 21, 2026

Close Date: November 19, 2026

Status: Posted

CFDA Numbers: 12.420

DoW Toxic Exposures Translational Research Award

Deadline: November 19, 2026


Opportunity Number: HT942526TERPTRA

Agency: Defense Health Agency Contracting Activity - DHACA

Open Date: May 21, 2026

Close Date: November 19, 2026

Status: Posted

CFDA Numbers: 12.420

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

Deadline: October 19, 2027


Opportunity Number: RFA-CA-27-019

Agency: National Institutes of Health

Open Date: May 21, 2026

Close Date: October 19, 2027

Status: Posted

CFDA Numbers: 93.399, 93.395, 93.393, 93.394, 93.396

Austrian-American Partnership Fund (AAPF)

Deadline: January 1, 2099


Opportunity Number: OFOP0002825

Agency: U.S. Mission to Austria

Open Date: May 20, 2026

Close Date: January 1, 2099

Status: Posted

CFDA Numbers: 19.040

F26AS00085 Aquatic Invasive Species Interjurisdictional Grants to the Great Lakes States and Tribes - Fiscal Year 2026 Great Lakes Restoration Initiative

Deadline: December 31, 2026


Opportunity Number: F26AS00085

Agency: Fish and Wildlife Service

Open Date: May 20, 2026

Close Date: December 31, 2026

Status: Posted

CFDA Numbers: 15.662

Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)

Deadline: August 21, 2028


Opportunity Number: RFA-DC-27-003

Agency: National Institutes of Health

Open Date: May 20, 2026

Close Date: August 21, 2028

Status: Posted

CFDA Numbers: 93.173, 93.286

Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)

Deadline: March 1, 2027


Opportunity Number: PAR-27-069

Agency: National Institutes of Health

Open Date: May 19, 2026

Close Date: March 1, 2027

Status: Posted

CFDA Numbers: 93.368

F25AS00332 Highlands Conservation Act – Competitive Funding Round

Deadline: October 31, 2026


Opportunity Number: F25AS00332

Agency: Fish and Wildlife Service

Open Date: May 19, 2026

Close Date: October 31, 2026

Status: Posted

CFDA Numbers: 15.667

F25AS00379 Highlands Conservation Act - Base Funding Round

Deadline: October 31, 2026


Opportunity Number: F25AS00379

Agency: Fish and Wildlife Service

Open Date: May 19, 2026

Close Date: October 31, 2026

Status: Posted

CFDA Numbers: 15.667

Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

Deadline: September 25, 2028


Opportunity Number: RFA-ES-27-004

Agency: National Institutes of Health

Open Date: May 19, 2026

Close Date: September 25, 2028

Status: Posted

CFDA Numbers: 93.143

Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)

Deadline: October 20, 2028


Opportunity Number: RFA-HD-27-007

Agency: National Institutes of Health

Open Date: May 19, 2026

Close Date: October 20, 2028

Status: Posted

CFDA Numbers: 93.242, 93.865

NASA Innovative Advanced Concepts (NIAC) Phase II

No deadline specified


Opportunity Number: NNH26ZTR001N-26NIAC-A2

Agency: NASA Headquarters

Open Date: May 14, 2026

Status: Posted

CFDA Numbers: 43.012

Title XVI Water Reclamation and Reuse Projects

Deadline: August 26, 2027


Opportunity Number: R26AS00079

Agency: Bureau of Reclamation

Open Date: May 14, 2026

Close Date: August 26, 2027

Status: Posted

CFDA Numbers: 15.504

WaterSMART Enhancing Water Resources Projects

Deadline: September 8, 2027


Opportunity Number: R26AS00017

Agency: Bureau of Reclamation

Open Date: May 14, 2026

Close Date: September 8, 2027

Status: Posted

CFDA Numbers: 15.507

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