Synopsis

CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.
Response Date	Jun 10, 2026 12:00:00 AM EDT
Posting Date	May 11, 2026 12:00:00 AM EDT
Archive Date	May 12, 2027 12:00:00 AM EDT
Award Ceiling	500,000
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

Others (see text field entitled "Additional Information on Eligibility" for clarification), City or township governments, Private institutions of higher education, Public housing authorities/Indian housing authorities, Native American tribal governments (Federally recognized), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility", County governments, Independent school districts, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Special district governments, State governments, Public and State controlled institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments)

Additional Info on Eligibility:

Additional Eligibility Information to be included in the NOFO.

Additional Information

Agency Name	Centers for Disease Control and Prevention - ERA
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 404-498-2015

CFDA Program(s)

• 93.061: Innovations in Applied Public Health Research