Synopsis

The purpose of component A (8-11 awardees) of this NOFO is to collect high-quality longitudinal data on children and adults with spina bifida (SB) who receive care in specialized spina bifida clinics participating in the National Spina Bifida Patient Registry (NSBPR). The purpose of component B (6-8 awardees) is to implement and evaluate the Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE) iterative protocol which aims to improve the management of the urinary and kidney systems in infants and young children with myelomeningocele. Building on existing longitudinal data collection, recipients will continue to collect data on patients with SB to better understand health outcomes after interventions and treatments, analyze the data and share findings to identify opportunities for improvement of care. An additional objective for Component B is to finalize the UMPIRE protocol for children 0-10 years old with myelomeningocele. Sources of data are specialty clinics that care for pediatric and adult patients with SB
Response Date	Oct 26, 2026 12:00:00 AM EDT
Posting Date	Aug 26, 2026 12:00:00 AM EDT
Archive Date	Nov 25, 2026 12:00:00 AM EST
Award Ceiling	300,000
Award Floor	100,000
Cost Sharing	No

Eligibility

Eligible Applicants

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Independent school districts, Small businesses, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Public and State controlled institutions of higher education, For profit organizations other than small businesses, Private institutions of higher education, Native American tribal governments (Federally recognized), Special district governments, County governments, City or township governments, State governments

Additional Info on Eligibility:

N/a

Additional Information

Agency Name	Centers for Disease Control - NCBDDD
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 7704882756

CFDA Program(s)

• 93.073: Birth Defects and Developmental Disabilities - Prevention and Surveillance