Synopsis

This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.
Response Date	Dec 01, 2030 12:00:00 AM EST
Posting Date	Oct 23, 2026 12:00:00 AM EDT
Archive Date	Feb 01, 2031 12:00:00 AM EST
Award Ceiling	N/a
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

County governments, Native American tribal governments (Federally recognized), Private institutions of higher education, For profit organizations other than small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public and State controlled institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Independent school districts, Small businesses, City or township governments, State governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Special district governments, Native American tribal organizations (other than Federally recognized tribal governments), Public housing authorities/Indian housing authorities

Additional Info on Eligibility:

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.121: Oral Diseases and Disorders Research
• 93.242: Mental Health Research Grants
• 93.273: Alcohol Research Programs
• 93.279: Drug Use and Addiction Research Programs
• 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health
• 93.853: Extramural Research Programs in the Neurosciences and Neurological Disorders
• 93.865: Child Health and Human Development Extramural Research
• 93.866: Aging Research
• 93.867: Vision Research